Abstract :Abstract
Background: This report presents the first case, to the authors’ knowledge, of tumor resection of a malignant deciduoidperitoneal mesothelioma producing granulocyte-colony stimulating factor (G-CSF).
Case Presentation: A 62-year-old man presented with a huge tumor located bilaterally over his entire abdominal cavity along with signs of fever and abdominal distension. Laboratory findings showed an increased white blood cell count and C-reactive protein level. The patient underwent surgical removal of the tumor along with tissue from the abdominal wall, and histopathological analysis led to a diagnosis of malignant peritoneal mesothelioma of the deciduoid type positive for G-CSF production based on serum level and immunohistochemical findings. Although the patient’s general condition quickly improved after surgery, local recurrence 7 months after the first chemotherapy treatment and 12 months after the first operation resulted in his death from the primary disease.
Conclusion: We report a very rare case of G-CSF-producing malignant peritoneal mesothelioma from the clinical course through to the valuable autopsy results.